diff --git a/monai/data/test_time_augmentation.py b/monai/data/test_time_augmentation.py
index bcd5ea91a9..e45b162f1f 100644
--- a/monai/data/test_time_augmentation.py
+++ b/monai/data/test_time_augmentation.py
@@ -68,7 +68,7 @@ class TestTimeAugmentation:
     Args:
         transform: transform (or composed) to be applied to each realization. At least one transform must be of type
         `RandomizableTrait` (i.e. `Randomizable`, `RandomizableTransform`, or `RandomizableTrait`).
-            . All random transforms must be of type `InvertibleTransform`.
+        All random transforms must be of type `InvertibleTransform`.
         batch_size: number of realizations to infer at once.
         num_workers: how many subprocesses to use for data.
         inferrer_fn: function to use to perform inference.
@@ -92,6 +92,11 @@ class TestTimeAugmentation:
             will return the full data. Dimensions will be same size as when passing a single image through
             `inferrer_fn`, with a dimension appended equal in size to `num_examples` (N), i.e., `[N,C,H,W,[D]]`.
         progress: whether to display a progress bar.
+        apply_inverse_to_pred: whether to apply inverse transformations to the predictions.
+            If the model's prediction is spatial (e.g. segmentation), this should be `True` to map the predictions
+            back to the original spatial reference.
+            If the prediction is non-spatial (e.g. classification label or score), this should be `False` to
+            aggregate the raw predictions directly. Defaults to `True`.
 
     Example:
         .. code-block:: python
@@ -125,6 +130,7 @@ def __init__(
         post_func: Callable = _identity,
         return_full_data: bool = False,
         progress: bool = True,
+        apply_inverse_to_pred: bool = True,
     ) -> None:
         self.transform = transform
         self.batch_size = batch_size
@@ -134,6 +140,7 @@ def __init__(
         self.image_key = image_key
         self.return_full_data = return_full_data
         self.progress = progress
+        self.apply_inverse_to_pred = apply_inverse_to_pred
         self._pred_key = CommonKeys.PRED
         self.inverter = Invertd(
             keys=self._pred_key,
@@ -199,7 +206,10 @@ def __call__(
         for b in tqdm(dl) if has_tqdm and self.progress else dl:
             # do model forward pass
             b[self._pred_key] = self.inferrer_fn(b[self.image_key].to(self.device))
-            outs.extend([self.inverter(PadListDataCollate.inverse(i))[self._pred_key] for i in decollate_batch(b)])
+            if self.apply_inverse_to_pred:
+                outs.extend([self.inverter(PadListDataCollate.inverse(i))[self._pred_key] for i in decollate_batch(b)])
+            else:
+                outs.extend([i[self._pred_key] for i in decollate_batch(b)])
 
         output: NdarrayOrTensor = stack(outs, 0)
 
diff --git a/tests/integration/test_testtimeaugmentation.py b/tests/integration/test_testtimeaugmentation.py
index 62e4b46282..84da7c9c15 100644
--- a/tests/integration/test_testtimeaugmentation.py
+++ b/tests/integration/test_testtimeaugmentation.py
@@ -104,7 +104,7 @@ def test_test_time_augmentation(self):
         # output might be different size, so pad so that they match
         train_loader = DataLoader(train_ds, batch_size=2, collate_fn=pad_list_data_collate)
 
-        model = UNet(2, 1, 1, channels=(6, 6), strides=(2, 2)).to(device)
+        model = UNet(2, 1, 1, channels=(6, 6), strides=(2,)).to(device)
         loss_function = DiceLoss(sigmoid=True)
         optimizer = torch.optim.Adam(model.parameters(), 1e-3)
 
@@ -181,6 +181,43 @@ def test_image_no_label(self):
         tta = TestTimeAugmentation(transforms, batch_size=5, num_workers=0, inferrer_fn=lambda x: x, orig_key="image")
         tta(self.get_data(1, (20, 20), include_label=False))
 
+    def test_non_spatial_output(self):
+        """
+        Test TTA for non-spatial output (e.g., classification scores).
+        Verifies that setting `apply_inverse_to_pred=False` correctly aggregates
+        predictions without attempting spatial inversion.
+        """
+        input_size = (20, 20)
+        data = {"image": np.random.rand(1, *input_size).astype(np.float32)}
+
+        transforms = Compose(
+            [EnsureChannelFirstd("image", channel_dim="no_channel"), RandFlipd("image", prob=1.0, spatial_axis=0)]
+        )
+
+        def mock_classifier(x):
+            batch_size = x.shape[0]
+            return torch.tensor([[0.2, 0.8]] * batch_size, dtype=torch.float32, device=x.device)
+
+        tt_aug = TestTimeAugmentation(
+            transform=transforms,
+            batch_size=2,
+            num_workers=0,
+            inferrer_fn=mock_classifier,
+            device="cpu",
+            orig_key="image",
+            apply_inverse_to_pred=False,
+            return_full_data=False,
+        )
+        mode, mean, std, vvc = tt_aug(data, num_examples=4)
+
+        self.assertEqual(mean.shape, (2,))
+        np.testing.assert_allclose(mean, [0.2, 0.8], atol=1e-6)
+        np.testing.assert_allclose(std, [0.0, 0.0], atol=1e-6)
+
+        tt_aug.return_full_data = True
+        full_output = tt_aug(data, num_examples=4)
+        self.assertEqual(full_output.shape, (4, 2))
+
 
 if __name__ == "__main__":
     unittest.main()