diff --git a/BioArchLinux/python-pyjess/PKGBUILD b/BioArchLinux/python-pyjess/PKGBUILD
new file mode 100644
index 0000000000..6593c6e776
--- /dev/null
+++ b/BioArchLinux/python-pyjess/PKGBUILD
@@ -0,0 +1,39 @@
+# Maintainer: Martin Larralde <martin.larralde@embl.de>
+
+_name=pyjess
+pkgname=python-${_name}
+pkgver=0.9.1
+pkgrel=1
+pkgdesc="Cython bindings and Python interface to Jess, a 3D template matching software."
+url="https://github.com/althonos/pyjess"
+arch=('i686' 'pentium4' 'x86_64' 'arm' 'armv6h' 'armv7h' 'aarch64')
+license=("MIT")
+depends=('python')
+makedepends=('cython' 'python-build' 'python-installer' 'cmake' 'ninja' 'python-scikit-build-core')
+source=("https://files.pythonhosted.org/packages/source/${_name::1}/$_name/$_name-$pkgver.tar.gz")
+sha256sums=(196630cd5dbd731d68bc74746acc8cf03e8b09c4c334f6e926ecc8ff352aeddd)
+
+build() {
+    cd "${srcdir}/${_name}-${pkgver}"
+    python -m build --wheel --no-isolation
+}
+
+check() {
+    local machine=$(python -c 'import platform; print(platform.machine())')
+    whl="${srcdir}/${_name}-${pkgver}/dist/${_name}-${pkgver}-cp38-abi3-linux_${machine}.whl"
+
+    if [ -e "${srcdir}/env" ]; then rm -rd "${srcdir}/env"; fi
+    python -m venv --symlinks --system-site-packages "${srcdir}/env"
+    source "${srcdir}/env/bin/activate"
+    python -m installer "$whl"
+
+    python -m unittest ${_name}.tests
+}
+
+package() {
+    local machine=$(python -c 'import platform; print(platform.machine())')
+    whl="${srcdir}/${_name}-${pkgver}/dist/${_name}-${pkgver}-cp38-abi3-linux_${machine}.whl"
+
+    python -m installer --prefix="${pkgdir}/usr" "$whl"
+    install -Dm644  "${srcdir}/${_name}-${pkgver}/COPYING" "$pkgdir/usr/share/licenses/$pkgname/COPYING"
+}
diff --git a/BioArchLinux/python-pyjess/lilac.yaml b/BioArchLinux/python-pyjess/lilac.yaml
new file mode 100644
index 0000000000..df28357f10
--- /dev/null
+++ b/BioArchLinux/python-pyjess/lilac.yaml
@@ -0,0 +1,14 @@
+maintainers:
+  - github: althonos
+    email: althonosdev@gmail.com
+build_prefix: extra-x86_64
+pre_build_script: |
+  update_pkgver_and_pkgrel(_G.newver.lstrip('v'))
+  run_cmd(['updpkgsums'])
+post_build_script: |
+  git_pkgbuild_commit()
+  update_aur_repo()
+update_on:
+  - source: pypi
+    pypi: pyjess
+  - alias: python